@article{Thompson2019327,
title = {A generic platform for the immobilisation of engineered biocatalysts},
author = {M P Thompson and S R Derrington and R S Heath and J L Porter and J Mangas-Sanchez and P N Devine and M D Truppo and N J Turner},
doi = {10.1016/j.tet.2018.12.004},
year = {2019},
date = {2019-01-01},
journal = {Tetrahedron},
volume = {75},
number = {3},
pages = {327-334},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Heath2019276,
title = {An Engineered Alcohol Oxidase for the Oxidation of Primary Alcohols},
author = {R S Heath and W R Birmingham and M P Thompson and A Taglieber and L Daviet and N J Turner},
doi = {10.1002/cbic.201800556},
year = {2019},
date = {2019-01-01},
journal = {ChemBioChem},
volume = {20},
number = {2},
pages = {276-281},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Thompson20199,
title = {Biocatalysis Using Immobilized Enzymes in Continuous Flow for the Synthesis of Fine Chemicals},
author = {M P Thompson and I Peñafiel and S C Cosgrove and N J Turner},
doi = {10.1021/acs.oprd.8b00305},
year = {2019},
date = {2019-01-01},
journal = {Organic Process Research and Development},
volume = {23},
number = {1},
pages = {9-18},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Ramsden20191201,
title = {Biocatalytic N-Alkylation of Amines Using Either Primary Alcohols or Carboxylic Acids via Reductive Aminase Cascades},
author = {J I Ramsden and R S Heath and S R Derrington and S L Montgomery and J Mangas-Sanchez and K R Mulholland and N J Turner},
doi = {10.1021/jacs.8b11561},
year = {2019},
date = {2019-01-01},
journal = {Journal of the American Chemical Society},
volume = {141},
number = {3},
pages = {1201-1206},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Megarity, C F; Siritanaratkul, B; Heath, R S; Wan, L; Morello, G; FitzPatrick, S R; Booth, R L; Sills, A J; Robertson, A W; Warner, J H; Turner, N J; Armstrong, F A
@article{Megarity20194948,
title = {Electrocatalytic Volleyball: Rapid Nanoconfined Nicotinamide Cycling for Organic Synthesis in Electrode Pores},
author = {C F Megarity and B Siritanaratkul and R S Heath and L Wan and G Morello and S R FitzPatrick and R L Booth and A J Sills and A W Robertson and J H Warner and N J Turner and F A Armstrong},
doi = {10.1002/anie.201814370},
year = {2019},
date = {2019-01-01},
journal = {Angewandte Chemie - International Edition},
volume = {58},
number = {15},
pages = {4948-4952},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Manning20195668,
title = {Regio- and Enantio-selective Chemo-enzymatic C−H-Lactonization of Decanoic Acid to (S)-δ-Decalactone},
author = {J Manning and M Tavanti and J L Porter and N Kress and S P De Visser and N J Turner and S L Flitsch},
doi = {10.1002/anie.201901242},
year = {2019},
date = {2019-01-01},
journal = {Angewandte Chemie - International Edition},
volume = {58},
number = {17},
pages = {5668-5671},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Parmeggiani20193482,
title = {One-Pot Biocatalytic Synthesis of Substituted d -Tryptophans from Indoles Enabled by an Engineered Aminotransferase},
author = {F Parmeggiani and A Rué Casamajo and C J W Walton and J L Galman and N J Turner and R A Chica},
doi = {10.1021/acscatal.9b00739},
year = {2019},
date = {2019-01-01},
journal = {ACS Catalysis},
volume = {9},
number = {4},
pages = {3482-3486},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Bornadel20191262,
title = {Technical Considerations for Scale-Up of Imine-Reductase-Catalyzed Reductive Amination: A Case Study},
author = {A Bornadel and S Bisagni and A Pushpanath and S L Montgomery and N J Turner and B Dominguez},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85067690635&doi=10.1021%2facs.oprd.9b00123&partnerID=40&md5=5f146067233716ead0a37d8e75ca2406},
doi = {10.1021/acs.oprd.9b00123},
year = {2019},
date = {2019-01-01},
journal = {Organic Process Research and Development},
volume = {23},
number = {6},
pages = {1262-1268},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Currin20191371,
title = {GeneORator: An Effective Strategy for Navigating Protein Sequence Space More Efficiently through Boolean OR-Type DNA Libraries},
author = {A Currin and J Kwok and J C Sadler and E L Bell and N Swainston and M Ababi and P Day and N J Turner and D B Kell},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85067556821&doi=10.1021%2facssynbio.9b00063&partnerID=40&md5=231ddfa9749bcdc560c28ee714e096a2},
doi = {10.1021/acssynbio.9b00063},
year = {2019},
date = {2019-01-01},
journal = {ACS Synthetic Biology},
volume = {8},
number = {6},
pages = {1371-1378},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{C9GC00270Gb,
title = {Synthesis of copper catalysts for click chemistry from distillery wastewater using magnetically recoverable bionanoparticles},
author = {Richard L Kimber and Fabio Parmeggiani and Nimisha Joshi and Alexander M Rakowski and Sarah J Haigh and Nicholas J Turner and Jonathan R Lloyd},
url = {http://dx.doi.org/10.1039/C9GC00270G},
doi = {10.1039/C9GC00270G},
year = {2019},
date = {2019-01-01},
journal = {Green Chem.},
volume = {21},
number = {15},
pages = {4020-4024},
publisher = {The Royal Society of Chemistry},
abstract = {Copper recovered from a whisky distillery waste stream is shown to be an effective catalyst for a range of azide–alkyne “click” reactions. Biogenic nanomagnetite (BNM), produced under mild conditions, was used to rapidly recover and subsequently support the Cu catalyst which could be separated and recycled easily.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Copper recovered from a whisky distillery waste stream is shown to be an effective catalyst for a range of azide–alkyne “click” reactions. Biogenic nanomagnetite (BNM), produced under mild conditions, was used to rapidly recover and subsequently support the Cu catalyst which could be separated and recycled easily.
@article{C9GC01902B,
title = {Biocatalytic retrosynthesis approaches to D-(2,4,5-trifluorophenyl)alanine, key precursor of the antidiabetic sitagliptin},
author = {Fabio Parmeggiani and Arnau Rué Casamajo and Danilo Colombo and Maria Chiara Ghezzi and James Louis Galman and Roberto A Chica and Elisabetta Brenna and Nicholas J Turner},
url = {http://dx.doi.org/10.1039/C9GC01902B},
doi = {10.1039/C9GC01902B},
year = {2019},
date = {2019-01-01},
journal = {Green Chem.},
volume = {21},
number = {16},
pages = {4368-4379},
publisher = {The Royal Society of Chemistry},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{C9CY01004A,
title = {Efficient synthesis of α-alkyl-β-amino amides by transaminase-mediated dynamic kinetic resolutions},
author = {Ángela Mourelle-Insua and Daniel Méndez-Sánchez and James L Galman and Iustina Slabu and Nicholas J Turner and Vicente Gotor-Fernández and Iván Lavandera},
url = {http://dx.doi.org/10.1039/C9CY01004A},
doi = {10.1039/C9CY01004A},
year = {2019},
date = {2019-01-01},
journal = {Catal. Sci. Technol.},
volume = {9},
number = {15},
pages = {4083-4090},
publisher = {The Royal Society of Chemistry},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Derrington201978,
title = {Carboxylic acid reductases (CARs): An industrial perspective},
author = {S R Derrington and N J Turner and S P France},
url = {https://www2.scopus.com/inward/record.uri?eid=2-s2.0-85071340147&doi=10.1016%2fj.jbiotec.2019.08.010&partnerID=40&md5=ea6571a1dcef953c31a326b0d8358b53},
doi = {10.1016/j.jbiotec.2019.08.010},
year = {2019},
date = {2019-01-01},
journal = {Journal of Biotechnology},
volume = {304},
pages = {78-88},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{C9GC01534E,
title = {Enzyme-catalysed enantioselective oxidation of alcohols by air exploiting fast electrochemical nicotinamide cycling in electrode nanopores},
author = {Lei Wan and Rachel S Heath and Bhavin Siritanaratkul and Clare F Megarity and Adam J Sills and Matthew P Thompson and Nicholas J Turner and Fraser A Armstrong},
url = {http://dx.doi.org/10.1039/C9GC01534E},
doi = {10.1039/C9GC01534E},
year = {2019},
date = {2019-01-01},
journal = {Green Chem.},
volume = {21},
number = {18},
pages = {4958-4963},
publisher = {The Royal Society of Chemistry},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Odachowski201810032,
title = {Concurrent Biocatalytic Oxidation and C-C Bond Formation via Gold Catalysis: One-Pot Alkynylation of N-Alkyl Tetrahydroisoquinolines},
author = {M Odachowski and M F Greaney and N J Turner},
doi = {10.1021/acscatal.8b03169},
year = {2018},
date = {2018-01-01},
journal = {ACS Catalysis},
volume = {8},
number = {11},
pages = {10032-10035},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Costa20184733,
title = {Synthesis of 2,5-Disubstituted Pyrrolidine Alkaloids via A One-Pot Cascade Using Transaminase and Reductive Aminase Biocatalysts},
author = {B Z Costa and J L Galman and I Slabu and S P France and A J Marsaioli and N J Turner},
doi = {10.1002/cctc.201801166},
year = {2018},
date = {2018-01-01},
journal = {ChemCatChem},
volume = {10},
number = {20},
pages = {4733-4738},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Toscani20188781,
title = {Monoamine Oxidase (MAO-N) Whole Cell Biocatalyzed Aromatization of 1,2,5,6-Tetrahydropyridines into Pyridines},
author = {A Toscani and C Risi and G W Black and N L Brown and A Shaaban and N J Turner and D Castagnolo},
doi = {10.1021/acscatal.8b02386},
year = {2018},
date = {2018-01-01},
journal = {ACS Catalysis},
volume = {8},
number = {9},
pages = {8781-8787},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Chapman201810535,
title = {Highly Productive Oxidative Biocatalysis in Continuous Flow by Enhancing the Aqueous Equilibrium Solubility of Oxygen},
author = {M R Chapman and S C Cosgrove and N J Turner and N Kapur and A J Blacker},
doi = {10.1002/anie.201803675},
year = {2018},
date = {2018-01-01},
journal = {Angewandte Chemie - International Edition},
volume = {57},
number = {33},
pages = {10535-10539},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Tavanti2018846,
title = {The crystal structure of P450-TT heme-domain provides the first structural insights into the versatile class VII P450s},
author = {M Tavanti and J L Porter and C W Levy and J R Gómez Castellanos and S L Flitsch and N J Turner},
doi = {10.1016/j.bbrc.2018.05.014},
year = {2018},
date = {2018-01-01},
journal = {Biochemical and Biophysical Research Communications},
volume = {501},
number = {4},
pages = {846-850},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Carbonell20182153,
title = {Selenzyme: Enzyme selection tool for pathway design},
author = {P Carbonell and J Wong and N Swainston and E Takano and N J Turner and N S Scrutton and D B Kell and R Breitling and J -L Faulon},
doi = {10.1093/bioinformatics/bty065},
year = {2018},
date = {2018-01-01},
journal = {Bioinformatics},
volume = {34},
number = {12},
pages = {2153-2154},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Cosgrove20185570,
title = {Synergistic Chemo/Biocatalytic Synthesis of Alkaloidal Tetrahydroquinolines},
author = {S C Cosgrove and S Hussain and N J Turner and S P Marsden},
doi = {10.1021/acscatal.8b01220},
year = {2018},
date = {2018-01-01},
journal = {ACS Catalysis},
volume = {8},
number = {6},
pages = {5570-5573},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Porter20181,
title = {Cloning, expression and characterisation of P450-Hal1 (CYP116B62) from Halomonas sp. NCIMB 172: A self-sufficient P450 with high expression and diverse substrate scope},
author = {J L Porter and S Sabatini and J Manning and M Tavanti and J L Galman and N J Turner and S L Flitsch},
doi = {10.1016/j.enzmictec.2018.02.005},
year = {2018},
date = {2018-01-01},
journal = {Enzyme and Microbial Technology},
volume = {113},
pages = {1-8},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Slabu201896,
title = {n-Butylamine as an alternative amine donor for the stereoselective biocatalytic transamination of ketones},
author = {I Slabu and J L Galman and C Iglesias and N J Weise and R C Lloyd and N J Turner},
doi = {10.1016/j.cattod.2017.01.025},
year = {2018},
date = {2018-01-01},
journal = {Catalysis Today},
volume = {306},
pages = {96-101},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Birmingham20184025,
title = {A Single Enzyme Oxidative “Cascade” via a Dual-Functional Galactose Oxidase},
author = {W R Birmingham and N J Turner},
doi = {10.1021/acscatal.8b00043},
year = {2018},
date = {2018-01-01},
journal = {ACS Catalysis},
volume = {8},
number = {5},
pages = {4025-4032},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Çakar2018327,
title = {Discovery of a new metal and NAD+-dependent formate dehydrogenase from Clostridium ljungdahlii},
author = {M M Çakar and J Mangas-Sanchez and W R Birmingham and N J Turner and B Binay},
doi = {10.1080/10826068.2018.1446150},
year = {2018},
date = {2018-01-01},
journal = {Preparative Biochemistry and Biotechnology},
volume = {48},
number = {4},
pages = {327-334},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Ahmed20183129,
title = {Engineered ammonia lyases for the production of challenging electron-rich l -phenylalanines},
author = {S T Ahmed and F Parmeggiani and N J Weise and S L Flitsch and N J Turner},
doi = {10.1021/acscatal.8b00496},
year = {2018},
date = {2018-01-01},
journal = {ACS Catalysis},
volume = {8},
number = {4},
pages = {3129-3132},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Turner2018A1,
title = {Editorial overview: Biocatalysis and biotransformation: The golden age of biocatalysis},
author = {N J Turner and R Kumar},
doi = {10.1016/j.cbpa.2018.02.012},
year = {2018},
date = {2018-01-01},
journal = {Current Opinion in Chemical Biology},
volume = {43},
pages = {A1-A3},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Weise2018288,
title = {Discovery and Investigation of Mutase-like Activity in a Phenylalanine Ammonia Lyase from Anabaena variabilis},
author = {N J Weise and F Parmeggiani and S T Ahmed and N J Turner},
doi = {10.1007/s11244-018-0898-1},
year = {2018},
date = {2018-01-01},
journal = {Topics in Catalysis},
volume = {61},
number = {3-4},
pages = {288-295},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Herter20181338,
title = {Mapping the substrate scope of monoamine oxidase (MAO-N) as a synthetic tool for the enantioselective synthesis of chiral amines},
author = {S Herter and F Medina and S Wagschal and C Benhaïm and F Leipold and N J Turner},
doi = {10.1016/j.bmc.2017.07.023},
year = {2018},
date = {2018-01-01},
journal = {Bioorganic and Medicinal Chemistry},
volume = {26},
number = {7},
pages = {1338-1346},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Morrill20183692,
title = {Biocatalytic Conversion of Cyclic Ketones Bearing α-Quaternary Stereocenters into Lactones in an Enantioselective Radical Approach to Medium-Sized Carbocycles},
author = {C Morrill and C Jensen and X Just-Baringo and G Grogan and N J Turner and D J Procter},
doi = {10.1002/anie.201800121},
year = {2018},
date = {2018-01-01},
journal = {Angewandte Chemie - International Edition},
volume = {57},
number = {14},
pages = {3692-3696},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Kimber, R L; Lewis, E A; Parmeggiani, F; Smith, K; Bagshaw, H; Starborg, T; Joshi, N; Figueroa, A I; van der Laan, G; Cibin, G; Gianolio, D; Haigh, S J; Pattrick, R A D; Turner, N J; Lloyd, J R
@article{Kimber2018,
title = {Biosynthesis and Characterization of Copper Nanoparticles Using Shewanella oneidensis: Application for Click Chemistry},
author = {R L Kimber and E A Lewis and F Parmeggiani and K Smith and H Bagshaw and T Starborg and N Joshi and A I Figueroa and G van der Laan and G Cibin and D Gianolio and S J Haigh and R A D Pattrick and N J Turner and J R Lloyd},
doi = {10.1002/smll.201703145},
year = {2018},
date = {2018-01-01},
journal = {Small},
volume = {14},
number = {10},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Tavanti20181042,
title = {Panel of New Thermostable CYP116B Self-Sufficient Cytochrome P450 Monooxygenases that Catalyze C−H Activation with a Diverse Substrate Scope},
author = {M Tavanti and J L Porter and S Sabatini and N J Turner and S L Flitsch},
doi = {10.1002/cctc.201701510},
year = {2018},
date = {2018-01-01},
journal = {ChemCatChem},
volume = {10},
number = {5},
pages = {1042-1051},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Porter2018513,
title = {Characterisation of CYP102A25 from Bacillus marmarensis and CYP102A26 from Pontibacillus halophilus: P450 Homologues of BM3 with Preference towards Hydroxylation of Medium-Chain Fatty Acids},
author = {J L Porter and J Manning and S Sabatini and M Tavanti and N J Turner and S L Flitsch},
doi = {10.1002/cbic.201700598},
year = {2018},
date = {2018-01-01},
journal = {ChemBioChem},
volume = {19},
number = {5},
pages = {513-520},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Barley2018234,
title = {Improved Descriptors for the Quantitative Structure-Activity Relationship Modeling of Peptides and Proteins},
author = {M H Barley and N J Turner and R Goodacre},
doi = {10.1021/acs.jcim.7b00488},
year = {2018},
date = {2018-01-01},
journal = {Journal of Chemical Information and Modeling},
volume = {58},
number = {2},
pages = {234-243},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{France2018510,
title = {Identification of Novel Bacterial Members of the Imine Reductase Enzyme Family that Perform Reductive Amination},
author = {S P France and R M Howard and J Steflik and N J Weise and J Mangas-Sanchez and S L Montgomery and R Crook and R Kumar and N J Turner},
doi = {10.1002/cctc.201701408},
year = {2018},
date = {2018-01-01},
journal = {ChemCatChem},
volume = {10},
number = {3},
pages = {510-514},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Aleku2018515,
title = {Kinetic Resolution and Deracemization of Racemic Amines Using a Reductive Aminase},
author = {G A Aleku and J Mangas-Sanchez and J Citoler and S P France and S L Montgomery and R S Heath and M P Thompson and N J Turner},
doi = {10.1002/cctc.201701484},
year = {2018},
date = {2018-01-01},
journal = {ChemCatChem},
volume = {10},
number = {3},
pages = {515-519},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Walton2018470,
title = {Engineered Aminotransferase for the Production of d-Phenylalanine Derivatives Using Biocatalytic Cascades},
author = {C J W Walton and F Parmeggiani and J E B Barber and J L McCann and N J Turner and R A Chica},
doi = {10.1002/cctc.201701068},
year = {2018},
date = {2018-01-01},
journal = {ChemCatChem},
volume = {10},
number = {2},
pages = {470-474},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Hutchings2018,
title = {Providing sustainable catalytic solutions for a rapidly changing world},
author = {G J Hutchings and C R Catlow and N J Turner},
doi = {10.1098/rsta.2017.0309},
year = {2018},
date = {2018-01-01},
journal = {Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences},
volume = {376},
number = {2110},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Aleku2018124,
title = {Biocatalytic Potential of Enzymes Involved in the Biosynthesis of Isoprenoid Quinones},
author = {G A Aleku and B Nowicka and N J Turner},
doi = {10.1002/cctc.201700685},
year = {2018},
date = {2018-01-01},
journal = {ChemCatChem},
volume = {10},
number = {1},
pages = {124-135},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Galman201811316,
title = {Biomimetic synthesis of 2-substituted N-heterocycle alkaloids by one-pot hydrolysis, transamination and decarboxylative Mannich reaction},
author = {J L Galman and I Slabu and F Parmeggiani and N J Turner},
doi = {10.1039/C8CC06759G},
year = {2018},
date = {2018-01-01},
journal = {Chemical Communications},
volume = {54},
number = {80},
pages = {11316-11319},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Parmeggiani201873,
title = {Synthetic and therapeutic applications of ammonia-lyases and aminomutases},
author = {F Parmeggiani and N J Weise and S T Ahmed and N J Turner},
doi = {10.1021/acs.chemrev.6b00824},
year = {2018},
date = {2018-01-01},
journal = {Chemical Reviews},
volume = {118},
number = {1},
pages = {73-118},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Klumbys2018658,
title = {Bio-derived production of cinnamyl alcohol: Via a three step biocatalytic cascade and metabolic engineering},
author = {E Klumbys and Z Zebec and N J Weise and N J Turner and N S Scrutton},
doi = {10.1039/c7gc03325g},
year = {2018},
date = {2018-01-01},
journal = {Green Chemistry},
volume = {20},
number = {3},
pages = {658-663},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Markošová2018127,
title = {Cloning and upscale production of monoamine oxidase N (MAO-N D5) by Pichia pastoris},
author = {K Markošová and A Camattari and M Rosenberg and A Glieder and N J Turner and M Rebroš},
doi = {10.1007/s10529-017-2450-y},
year = {2018},
date = {2018-01-01},
journal = {Biotechnology Letters},
volume = {40},
number = {1},
pages = {127-133},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Sharma201811534,
title = {A Mechanism for Reductive Amination Catalyzed by Fungal Reductive Aminases},
author = {M Sharma and J Mangas-Sanchez and S P France and G A Aleku and S L Montgomery and J I Ramsden and N J Turner and G Grogan},
doi = {10.1021/acscatal.8b03491},
year = {2018},
date = {2018-01-01},
journal = {ACS Catalysis},
pages = {11534-11541},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Cosgrove2018131,
title = {Imine Reductases, Reductive Aminases, and Amine Oxidases for the Synthesis of Chiral Amines: Discovery, Characterization, and Synthetic Applications},
author = {S C Cosgrove and A Brzezniak and S P France and J I Ramsden and J Mangas-Sanchez and S L Montgomery and R S Heath and N J Turner},
doi = {10.1016/bs.mie.2018.04.022},
year = {2018},
date = {2018-01-01},
journal = {Methods in Enzymology},
volume = {608},
pages = {131-149},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Batista201811889,
title = {Monoamine Oxidase: Tunable Activity for Amine Resolution and Functionalization},
author = {V F Batista and J L Galman and D C Pinto and A M S Silva and N J Turner},
doi = {10.1021/acscatal.8b03525},
year = {2018},
date = {2018-01-01},
journal = {ACS Catalysis},
volume = {8},
number = {12},
pages = {11889-11907},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Xu201816760,
title = {Chemo-Enzymatic Synthesis of Pyrazines and Pyrroles},
author = {J Xu and A P Green and N J Turner},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85057010763&doi=10.1002%2fanie.201810555&partnerID=40&md5=a3353cb0471575cf34876f6915950255},
doi = {10.1002/anie.201810555},
year = {2018},
date = {2018-01-01},
journal = {Angewandte Chemie - International Edition},
volume = {57},
number = {51},
pages = {16760-16763},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Devine2018409,
title = {Extending the application of biocatalysis to meet the challenges of drug development},
author = {P N Devine and R M Howard and R Kumar and M P Thompson and M D Truppo and N J Turner},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85060102129&doi=10.1038%2fs41570-018-0055-1&partnerID=40&md5=66093a04b19e180f6ca493bbc85c9d76},
doi = {10.1038/s41570-018-0055-1},
year = {2018},
date = {2018-01-01},
journal = {Nature Reviews Chemistry},
volume = {2},
number = {12},
pages = {409-421},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@book{Burke20181,
title = {Active pharmaceutical ingredients in synthesis: Catalytic processes in research and development},
author = {A J Burke and C S Marques and N J Turner and G J Hermann},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85060529666&doi=10.1002%2f9783527807253&partnerID=40&md5=885f37990332e0db06c2dc8b78854f82},
doi = {10.1002/9783527807253},
year = {2018},
date = {2018-01-01},
journal = {Active Pharmaceutical Ingredients in Synthesis: Catalytic Processes in Research and Development},
pages = {1-426},
keywords = {},
pubstate = {published},
tppubtype = {book}
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@article{Zawodny201817872,
title = {Chemoenzymatic Synthesis of Substituted Azepanes by Sequential Biocatalytic Reduction and Organolithium-Mediated Rearrangement},
author = {W Zawodny and S L Montgomery and J R Marshall and J D Finnigan and N J Turner and J Clayden},
doi = {10.1021/jacs.8b11891},
year = {2018},
date = {2018-01-01},
journal = {Journal of the American Chemical Society},
volume = {140},
number = {51},
pages = {17872-17877},
note = {cited By 0},
keywords = {},
pubstate = {published},
tppubtype = {article}
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France, S P; Aleku, G A; Sharma, M; Mangas-Sanchez, J; Howard, R M; Steflik, J; Kumar, R; Adams, R W; Slabu, I; Crook, R; Grogan, G; Wallace, T W; Turner, N J
@article{France201715589,
title = {Biocatalytic Routes to Enantiomerically Enriched Dibenz[c,e]azepines},
author = {S P France and G A Aleku and M Sharma and J Mangas-Sanchez and R M Howard and J Steflik and R Kumar and R W Adams and I Slabu and R Crook and G Grogan and T W Wallace and N J Turner},
doi = {10.1002/anie.201708453},
year = {2017},
date = {2017-01-01},
journal = {Angewandte Chemie - International Edition},
volume = {56},
number = {49},
pages = {15589-15593},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Slabu20178263,
title = {Discovery, Engineering, and Synthetic Application of Transaminase Biocatalysts},
author = {I Slabu and J L Galman and R C Lloyd and N J Turner},
doi = {10.1021/acscatal.7b02686},
year = {2017},
date = {2017-01-01},
journal = {ACS Catalysis},
volume = {7},
number = {12},
pages = {8263-8284},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Weise2017,
title = {Zymophore identification enables the discovery of novel phenylalanine ammonia lyase enzymes},
author = {N J Weise and S T Ahmed and F Parmeggiani and J L Galman and M S Dunstan and S J Charnock and D Leys and N J Turner},
doi = {10.1038/s41598-017-13990-0},
year = {2017},
date = {2017-01-01},
journal = {Scientific Reports},
volume = {7},
number = {1},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Fisk201712527,
title = {From Multistep Enzyme Monitoring to Whole-Cell Biotransformations: Development of Real-Time Ultraviolet Resonance Raman Spectroscopy},
author = {H Fisk and Y Xu and C Westley and N J Turner and J Micklefield and R Goodacre},
doi = {10.1021/acs.analchem.7b03742},
year = {2017},
date = {2017-01-01},
journal = {Analytical Chemistry},
volume = {89},
number = {22},
pages = {12527-12532},
keywords = {},
pubstate = {published},
tppubtype = {article}
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Wood, A J L; Weise, N J; Frampton, J D; Dunstan, M S; Hollas, M A; Derrington, S R; Lloyd, R C; Quaglia, D; Parmeggiani, F; Leys, D; Turner, N J; Flitsch, S L
@article{Wood201714498,
title = {Adenylation Activity of Carboxylic Acid Reductases Enables the Synthesis of Amides},
author = {A J L Wood and N J Weise and J D Frampton and M S Dunstan and M A Hollas and S R Derrington and R C Lloyd and D Quaglia and F Parmeggiani and D Leys and N J Turner and S L Flitsch},
doi = {10.1002/anie.201707918},
year = {2017},
date = {2017-01-01},
journal = {Angewandte Chemie - International Edition},
volume = {56},
number = {46},
pages = {14498-14501},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Hartley2017,
title = {Sugar analog synthesis by in vitro biocatalytic cascade: A comparison of alternative enzyme complements for dihydroxyacetone phosphate production as a precursor to rare chiral sugar synthesis},
author = {C J Hartley and N G French and J A Scoble and C C Williams and Q I Churches and A R Frazer and M C Taylor and G Coia and G Simpson and N J Turner and C Scott},
doi = {10.1371/journal.pone.0184183},
year = {2017},
date = {2017-01-01},
journal = {PLoS ONE},
volume = {12},
number = {11},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Thompson20173833,
title = {Two-Enzyme Hydrogen-Borrowing Amination of Alcohols Enabled by a Cofactor-Switched Alcohol Dehydrogenase},
author = {M P Thompson and N J Turner},
doi = {10.1002/cctc.201701092},
year = {2017},
date = {2017-01-01},
journal = {ChemCatChem},
volume = {9},
number = {20},
pages = {3833-3836},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Aleku2017961,
title = {A reductive aminase from Aspergillus oryzae},
author = {G A Aleku and S P France and H Man and J Mangas-Sanchez and S L Montgomery and M Sharma and F Leipold and S Hussain and G Grogan and N J Turner},
doi = {10.1038/nchem.2782},
year = {2017},
date = {2017-01-01},
journal = {Nature Chemistry},
volume = {9},
number = {10},
pages = {961-969},
keywords = {},
pubstate = {published},
tppubtype = {article}
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Chapman, M R; Kwan, M H T; King, G; Jolley, K E; Hussain, M; Hussain, S; Salama, I E; Nino, González C; Thompson, L A; Bayana, M E; Clayton, A D; Nguyen, B N; Turner, N J; Kapur, N; Blacker, A J
@article{Chapman20171294,
title = {Simple and Versatile Laboratory Scale CSTR for Multiphasic Continuous-Flow Chemistry and Long Residence Times},
author = {M R Chapman and M H T Kwan and G King and K E Jolley and M Hussain and S Hussain and I E Salama and C González Nino and L A Thompson and M E Bayana and A D Clayton and B N Nguyen and N J Turner and N Kapur and A J Blacker},
doi = {10.1021/acs.oprd.7b00173},
year = {2017},
date = {2017-01-01},
journal = {Organic Process Research and Development},
volume = {21},
number = {9},
pages = {1294-1301},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Tavanti20173338,
title = {One-Pot Biocatalytic Double Oxidation of α-Isophorone for the Synthesis of Ketoisophorone},
author = {M Tavanti and F Parmeggiani and J R G Castellanos and A Mattevi and N J Turner},
doi = {10.1002/cctc.201700620},
year = {2017},
date = {2017-01-01},
journal = {ChemCatChem},
volume = {9},
number = {17},
pages = {3338-3348},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Ahmed201730,
title = {Applications of phenylalanine ammonia lyases in synthesis: Access to enantiopure arylalanines from laboratory scale to industrial production},
author = {S T Ahmed and N J Weise and F Parmeggiani and N J Turner},
url = {https://www.teknoscienze.com/tks_article/applications-of-phenylalanine-ammonia-lyases-in-synthesis/},
year = {2017},
date = {2017-01-01},
journal = {Chimica Oggi/Chemistry Today},
volume = {35},
number = {5},
pages = {30-33},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Gahloth2017975,
title = {Structures of carboxylic acid reductase reveal domain dynamics underlying catalysis},
author = {D Gahloth and M S Dunstan and D Quaglia and E Klumbys and M P Lockhart-Cairns and A M Hill and S R Derrington and N S Scrutton and N J Turner and D Leys},
doi = {10.1038/nchembio.2434},
year = {2017},
date = {2017-01-01},
journal = {Nature Chemical Biology},
volume = {13},
number = {9},
pages = {975-981},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Zajkoska20171558,
title = {Chemo-biocatalytic one-pot two-step conversion of cyclic amine to lactam using whole cell monoamine oxidase},
author = {P Zajkoska and M Cárdenas-Fernández and G J Lye and M Rosenberg and N J Turner and M Rebroš},
doi = {10.1002/jctb.5146},
year = {2017},
date = {2017-01-01},
journal = {Journal of Chemical Technology and Biotechnology},
volume = {92},
number = {7},
pages = {1558-1565},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Barley20171087,
title = {Recommendations on the Implementation of Genetic Algorithms for the Directed Evolution of Enzymes for Industrial Purposes},
author = {M H Barley and N J Turner and R Goodacre},
doi = {10.1002/cbic.201700013},
year = {2017},
date = {2017-01-01},
journal = {ChemBioChem},
volume = {18},
number = {12},
pages = {1087-1097},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Sharma20172011,
title = {NAD(P)H-Dependent Dehydrogenases for the Asymmetric Reductive Amination of Ketones: Structure, Mechanism, Evolution and Application},
author = {M Sharma and J Mangas-Sanchez and N J Turner and G Grogan},
doi = {10.1002/adsc.201700356},
year = {2017},
date = {2017-01-01},
journal = {Advanced Synthesis and Catalysis},
volume = {359},
number = {12},
pages = {2011-2025},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Weise20171570,
title = {Kinetic Resolution of Aromatic β-Amino Acids Using a Combination of Phenylalanine Ammonia Lyase and Aminomutase Biocatalysts},
author = {N J Weise and S T Ahmed and F Parmeggiani and N J Turner},
doi = {10.1002/adsc.201600894},
year = {2017},
date = {2017-01-01},
journal = {Advanced Synthesis and Catalysis},
volume = {359},
number = {9},
pages = {1570-1576},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Hepworth20172920,
title = {Enzyme Cascades in Whole Cells for the Synthesis of Chiral Cyclic Amines},
author = {L J Hepworth and S P France and S Hussain and P Both and N J Turner and S L Flitsch},
doi = {10.1021/acscatal.7b00513},
year = {2017},
date = {2017-01-01},
journal = {ACS Catalysis},
volume = {7},
number = {4},
pages = {2920-2925},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Mangas-Sanchez201719,
title = {Imine reductases (IREDs)},
author = {J Mangas-Sanchez and S P France and S L Montgomery and G A Aleku and H Man and M Sharma and J I Ramsden and G Grogan and N J Turner},
doi = {10.1016/j.cbpa.2016.11.022},
year = {2017},
date = {2017-01-01},
journal = {Current Opinion in Chemical Biology},
volume = {37},
pages = {19-25},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Klenk2017,
title = {The self-sufficient P450 RhF expressed in a whole cell system selectively catalyses the 5-hydroxylation of diclofenac},
author = {J M Klenk and B A Nebel and J L Porter and J K Kulig and S A Hussain and S M Richter and M Tavanti and N J Turner and M A Hayes and B Hauer and S L Flitsch},
doi = {10.1002/biot.201600520},
year = {2017},
date = {2017-01-01},
journal = {Biotechnology Journal},
volume = {12},
number = {3},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Westley20172472,
title = {Absolute Quantification of Uric Acid in Human Urine Using Surface Enhanced Raman Scattering with the Standard Addition Method},
author = {C Westley and Y Xu and B Thilaganathan and A J Carnell and N J Turner and R Goodacre},
doi = {10.1021/acs.analchem.6b04588},
year = {2017},
date = {2017-01-01},
journal = {Analytical Chemistry},
volume = {89},
number = {4},
pages = {2472-2477},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Hugentobler2017195,
title = {Comparison of a Batch and Flow Approach for the Lipase-Catalyzed Resolution of a Cyclopropanecarboxylate Ester, A Key Building Block for the Synthesis of Ticagrelor},
author = {K G Hugentobler and M Rasparini and L A Thompson and K E Jolley and A J Blacker and N J Turner},
doi = {10.1021/acs.oprd.6b00346},
year = {2017},
date = {2017-01-01},
journal = {Organic Process Research and Development},
volume = {21},
number = {2},
pages = {195-199},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Scalacci20171295,
title = {Unveiling the Biocatalytic Aromatizing Activity of Monoamine Oxidases MAO-N and 6-HDNO: Development of Chemoenzymatic Cascades for the Synthesis of Pyrroles},
author = {N Scalacci and G W Black and G Mattedi and N L Brown and N J Turner and D Castagnolo},
doi = {10.1021/acscatal.6b03081},
year = {2017},
date = {2017-01-01},
journal = {ACS Catalysis},
volume = {7},
number = {2},
pages = {1295-1300},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Yan20171408,
title = {Real-time screening of biocatalysts in live bacterial colonies},
author = {C Yan and F Parmeggiani and E A Jones and E Claude and S A Hussain and N J Turner and S L Flitsch and P E Barran},
doi = {10.1021/jacs.6b12165},
year = {2017},
date = {2017-01-01},
journal = {Journal of the American Chemical Society},
volume = {139},
number = {4},
pages = {1408-1411},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{France2017710,
title = {Constructing Biocatalytic Cascades: In Vitro and in Vivo Approaches to de Novo Multi-Enzyme Pathways},
author = {S P France and L J Hepworth and N J Turner and S L Flitsch},
doi = {10.1021/acscatal.6b02979},
year = {2017},
date = {2017-01-01},
journal = {ACS Catalysis},
volume = {7},
number = {1},
pages = {710-724},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Hönig20178942,
title = {Enantioselective Chemo- and Biocatalysis: Partners in Retrosynthesis},
author = {M Hönig and P Sondermann and N J Turner and E M Carreira},
doi = {10.1002/anie.201612462},
year = {2017},
date = {2017-01-01},
journal = {Angewandte Chemie - International Edition},
volume = {56},
number = {31},
pages = {8942-8973},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Tavanti20179790,
title = {A biocatalytic cascade for the amination of unfunctionalised cycloalkanes},
author = {M Tavanti and J Mangas-Sanchez and S L Montgomery and M P Thompson and N J Turner},
doi = {10.1039/c7ob02569f},
year = {2017},
date = {2017-01-01},
journal = {Organic and Biomolecular Chemistry},
volume = {15},
number = {46},
pages = {9790-9793},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@book{Hutchings20171,
title = {Modern developments in catalysis},
author = {G Hutchings and M Davidson and R Catlow and C Hardacre and N Turner and P Collier},
doi = {10.1142/q0035},
year = {2017},
date = {2017-01-01},
journal = {Modern Developments in Catalysis},
pages = {1-320},
keywords = {},
pubstate = {published},
tppubtype = {book}
}
@article{Galman2017361,
title = {Biocatalytic transamination with near-stoichiometric inexpensive amine donors mediated by bifunctional mono- and di-amine transaminases},
author = {J L Galman and I Slabu and N J Weise and C Iglesias and F Parmeggiani and R C Lloyd and N J Turner},
doi = {10.1039/c6gc02102f},
year = {2017},
date = {2017-01-01},
journal = {Green Chemistry},
volume = {19},
number = {2},
pages = {361-366},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Weissenborn2017742,
title = {Development of a solid phase array assay for the screening of galactose oxidase activity and for fast identification of inhibitors},
author = {M J Weissenborn and D P Debecker and S Golten and B Linclau and N J Turner and S L Flitsch},
doi = {10.2174/0929866524666170724114348},
year = {2017},
date = {2017-01-01},
journal = {Protein and Peptide Letters},
volume = {24},
number = {8},
pages = {742-746},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Aslan201747,
title = {Chaetomium thermophilum formate dehydrogenase has high activity in the reduction of hydrogen carbonate (HCO3 -) to formate},
author = {A S Aslan and J Valjakka and J Ruupunen and D Yildirim and N J Turner and O Turunen and B Binay},
doi = {10.1093/protein/gzw062},
year = {2017},
date = {2017-01-01},
journal = {Protein engineering, design & selection : PEDS},
volume = {30},
number = {1},
pages = {47-55},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Montgomery201710491,
title = {Direct Alkylation of Amines with Primary and Secondary Alcohols through Biocatalytic Hydrogen Borrowing},
author = {S L Montgomery and J Mangas-Sanchez and M P Thompson and G A Aleku and B Dominguez and N J Turner},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85025447057&doi=10.1002%2fanie.201705848&partnerID=40&md5=eed24e7ae2f636451659a45758dd448d},
doi = {10.1002/anie.201705848},
year = {2017},
date = {2017-01-01},
journal = {Angewandte Chemie - International Edition},
volume = {56},
number = {35},
pages = {10491-10494},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Westley20176983,
title = {Real-Time Monitoring of Enzyme-Catalysed Reactions using Deep UV Resonance Raman Spectroscopy},
author = {C Westley and H Fisk and Y Xu and K A Hollywood and A J Carnell and J Micklefield and N J Turner and R Goodacre},
doi = {10.1002/chem.201701388},
year = {2017},
date = {2017-01-01},
journal = {Chemistry - A European Journal},
volume = {23},
number = {29},
pages = {6983-6987},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{McKenna20174660,
title = {The continuous oxidation of HMF to FDCA and the immobilisation and stabilisation of periplasmic aldehyde oxidase (PaoABC)},
author = {S M McKenna and P Mines and P Law and K Kovacs-Schreiner and W R Birmingham and N J Turner and S Leimkühler and A J Carnell},
doi = {10.1039/c7gc01696d},
year = {2017},
date = {2017-01-01},
journal = {Green Chemistry},
volume = {19},
number = {19},
pages = {4660-4665},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Ahmed20165468,
title = {Synthesis of Enantiomerically Pure Ring-Substituted l -Pyridylalanines by Biocatalytic Hydroamination},
author = {S T Ahmed and F Parmeggiani and N J Weise and S L Flitsch and N J Turner},
doi = {10.1021/acs.orglett.6b02559},
year = {2016},
date = {2016-01-01},
journal = {Organic Letters},
volume = {18},
number = {21},
pages = {5468-5471},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{VanOosterwijk20164422,
title = {Structural Basis of the Substrate Range and Enantioselectivity of Two (S)-Selective ω-Transaminases},
author = {N Van Oosterwijk and S Willies and J Hekelaar and A C Terwisscha Van Scheltinga and N J Turner and B W Dijkstra},
doi = {10.1021/acs.biochem.6b00370},
year = {2016},
date = {2016-01-01},
journal = {Biochemistry},
volume = {55},
number = {31},
pages = {4422-4431},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Markošová201669,
title = {Immobilisation and kinetics of monoamine oxidase (MAO-N-D5) enzyme in polyvinyl alcohol gels},
author = {K Markošová and I Dolejš and R Stloukal and L Rios-Solis and M Rosenberg and M Micheletti and G J Lye and N J Turner and M Rebroš},
doi = {10.1016/j.molcatb.2016.04.009},
year = {2016},
date = {2016-01-01},
journal = {Journal of Molecular Catalysis B: Enzymatic},
volume = {129},
pages = {69-74},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Carbonell2016675,
title = {SYNBIOCHEM - A SynBio foundry for the biosynthesis and sustainable production of fine and speciality chemicals},
author = {P Carbonell and A Currin and M Dunstan and D Fellows and A Jervis and N J W Rattray and C J Robinson and N Swainston and M Vinaixa and A Williams and C Yan and P Barran and R Breitling and G G -Q Chen and J -L Faulon and C Goble and R Goodacre and D B Kell and R L Feuvre and J Micklefield and N S Scrutton and P Shapira and E Takano and N J Turner},
doi = {10.1042/BST20160009},
year = {2016},
date = {2016-01-01},
journal = {Biochemical Society Transactions},
volume = {44},
number = {3},
pages = {675-677},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Westley20165898,
title = {Label-Free Surface Enhanced Raman Scattering Approach for High-Throughput Screening of Biocatalysts},
author = {C Westley and Y Xu and A J Carnell and N J Turner and R Goodacre},
doi = {10.1021/acs.analchem.6b00813},
year = {2016},
date = {2016-01-01},
journal = {Analytical Chemistry},
volume = {88},
number = {11},
pages = {5898-5903},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{France20163753,
title = {One-Pot Cascade Synthesis of Mono- and Disubstituted Piperidines and Pyrrolidines using Carboxylic Acid Reductase (CAR), ω-Transaminase (ω-TA), and Imine Reductase (IRED) Biocatalysts},
author = {S P France and S Hussain and A M Hill and L J Hepworth and R M Howard and K R Mulholland and S L Flitsch and N J Turner},
doi = {10.1021/acscatal.6b00855},
year = {2016},
date = {2016-01-01},
journal = {ACS Catalysis},
volume = {6},
number = {6},
pages = {3753-3759},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Aleku20163880,
title = {Stereoselectivity and Structural Characterization of an Imine Reductase (IRED) from Amycolatopsis orientalis},
author = {G A Aleku and H Man and S P France and F Leipold and S Hussain and L Toca-Gonzalez and R Marchington and S Hart and J P Turkenburg and G Grogan and N J Turner},
doi = {10.1021/acscatal.6b00782},
year = {2016},
date = {2016-01-01},
journal = {ACS Catalysis},
volume = {6},
number = {6},
pages = {3880-3889},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Aslan2016474,
title = {Semi-Rational Design of Geobacillus stearothermophilus L-Lactate Dehydrogenase to Access Various Chiral α-Hydroxy Acids},
author = {A S Aslan and W R Birmingham and N G Karagüler and N J Turner and B Binay},
doi = {10.1007/s12010-016-2007-x},
year = {2016},
date = {2016-01-01},
journal = {Applied Biochemistry and Biotechnology},
volume = {179},
number = {3},
pages = {474-484},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Yan20162351,
title = {Rapid and sensitive monitoring of biocatalytic reactions using ion mobility mass spectrometry},
author = {C Yan and J W Schmidberger and F Parmeggiani and S A Hussain and N J Turner and S L Flitsch and P Barran},
doi = {10.1039/c6an00617e},
year = {2016},
date = {2016-01-01},
journal = {Analyst},
volume = {141},
number = {8},
pages = {2351-2355},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Slabu20161038,
title = {Putrescine Transaminases for the Synthesis of Saturated Nitrogen Heterocycles from Polyamines},
author = {I Slabu and J L Galman and N J Weise and R C Lloyd and N J Turner},
doi = {10.1002/cctc.201600075},
year = {2016},
date = {2016-01-01},
journal = {ChemCatChem},
volume = {8},
number = {6},
pages = {1038-1042},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Wells, A S; Wong, J W; Michels, P C; Entwistle, D A; Fandrick, K; Finch, G L; Goswami, A; Lee, H; Mix, S; Moody, T S; Pang, L; Sato, R K; Turner, N J; Watson, T J
@article{Wells2016594,
title = {Case Studies Illustrating a Science and Risk-Based Approach to Ensuring Drug Quality When Using Enzymes in the Manufacture of Active Pharmaceuticals Ingredients for Oral Dosage Form},
author = {A S Wells and J W Wong and P C Michels and D A Entwistle and K Fandrick and G L Finch and A Goswami and H Lee and S Mix and T S Moody and L Pang and R K Sato and N J Turner and T J Watson},
doi = {10.1021/acs.oprd.5b00369},
year = {2016},
date = {2016-01-01},
journal = {Organic Process Research and Development},
volume = {20},
number = {3},
pages = {594-601},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Eichler2016426,
title = {Enantioselective Benzylic Hydroxylation Catalysed by P450 Monooxygenases: Characterisation of a P450cam Mutant Library and Molecular Modelling},
author = {A Eichler and Ł Gricman and S Herter and P P Kelly and N J Turner and J Pleiss and S L Flitsch},
doi = {10.1002/cbic.201500536},
year = {2016},
date = {2016-01-01},
journal = {ChemBioChem},
volume = {17},
number = {5},
pages = {426-432},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Willies2016,
title = {A stereospecific solid-phase screening assay for colonies expressing both (R)-and (S)-selective Ω-Aminotransferases},
author = {S C Willies and J L Galman and I Slabu and N J Turner},
doi = {10.1098/rsta.2015.0084},
year = {2016},
date = {2016-01-01},
journal = {Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences},
volume = {374},
number = {2061},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Grogan20161900,
title = {InspIRED by Nature: NADPH-Dependent Imine Reductases (IREDs) as Catalysts for the Preparation of Chiral Amines},
author = {G Grogan and N J Turner},
doi = {10.1002/chem.201503954},
year = {2016},
date = {2016-01-01},
journal = {Chemistry - A European Journal},
volume = {22},
number = {6},
pages = {1900-1907},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Both20161511,
title = {Whole-Cell Biocatalysts for Stereoselective C-H Amination Reactions},
author = {P Both and H Busch and P P Kelly and F G Mutti and N J Turner and S L Flitsch},
doi = {10.1002/anie.201510028},
year = {2016},
date = {2016-01-01},
journal = {Angewandte Chemie - International Edition},
volume = {55},
number = {4},
pages = {1511-1513},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Heath2016117,
title = {Combined Imine Reductase and Amine Oxidase Catalyzed Deracemization of Nitrogen Heterocycles},
author = {R S Heath and M Pontini and S Hussain and N J Turner},
doi = {10.1002/cctc.201500822},
year = {2016},
date = {2016-01-01},
journal = {ChemCatChem},
volume = {8},
number = {1},
pages = {117-120},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Fisk201659,
title = {Achieving optimal SERS through enhanced experimental design},
author = {H Fisk and C Westley and N J Turner and R Goodacre},
doi = {10.1002/jrs.4855},
year = {2016},
date = {2016-01-01},
journal = {Journal of Raman Spectroscopy},
volume = {47},
number = {1},
pages = {59-66},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Roselló20165172,
title = {Substituent effects on axial chirality in 1-aryl-3,4-dihydroisoquinolines: controlling the rate of bond rotation},
author = {J M Roselló and S Staniland and N J Turner and J Clayden},
doi = {10.1016/j.tet.2016.01.037},
year = {2016},
date = {2016-01-01},
journal = {Tetrahedron},
volume = {72},
number = {34},
pages = {5172-5177},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Parmeggiani20167256,
title = {Telescopic one-pot condensation-hydroamination strategy for the synthesis of optically pure L-phenylalanines from benzaldehydes},
author = {F Parmeggiani and S T Ahmed and N J Weise and N J Turner},
doi = {10.1016/j.tet.2015.12.063},
year = {2016},
date = {2016-01-01},
journal = {Tetrahedron},
volume = {72},
number = {46},
pages = {7256-7262},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Hugentobler20168064,
title = {Biocatalytic approaches to a key building block for the anti-thrombotic agent ticagrelor},
author = {K G Hugentobler and H Sharif and M Rasparini and R S Heath and N J Turner},
doi = {10.1039/c6ob01382a},
year = {2016},
date = {2016-01-01},
journal = {Organic and Biomolecular Chemistry},
volume = {14},
number = {34},
pages = {8064-8067},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Rowles20167343,
title = {Engineering of phenylalanine ammonia lyase from Rhodotorula graminis for the enhanced synthesis of unnatural L-amino acids},
author = {I Rowles and B Groenendaal and B Binay and K J Malone and S C Willies and N J Turner},
doi = {10.1016/j.tet.2016.06.026},
year = {2016},
date = {2016-01-01},
journal = {Tetrahedron},
volume = {72},
number = {46},
pages = {7343-7347},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Weise20164086,
title = {Intensified biocatalytic production of enantiomerically pure halophenylalanines from acrylic acids using ammonium carbamate as the ammonia source},
author = {N J Weise and S T Ahmed and F Parmeggiani and E Siirola and A Pushpanath and U Schell and N J Turner},
doi = {10.1039/c6cy00855k},
year = {2016},
date = {2016-01-01},
journal = {Catalysis Science and Technology},
volume = {6},
number = {12},
pages = {4086-4089},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Parmeggiani20163298,
title = {Single-Biocatalyst Synthesis of Enantiopure d-Arylalanines Exploiting an Engineered d-Amino Acid Dehydrogenase},
author = {F Parmeggiani and S T Ahmed and M P Thompson and N J Weise and J L Galman and D Gahloth and M S Dunstan and D Leys and N J Turner},
doi = {10.1002/adsc.201600682},
year = {2016},
date = {2016-01-01},
journal = {Advanced Synthesis and Catalysis},
volume = {358},
number = {20},
pages = {3298-3306},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Weissenborn20166158,
title = {Whole-cell microtiter plate screening assay for terminal hydroxylation of fatty acids by P450s},
author = {M J Weissenborn and S Notonier and S -L Lang and K B Otte and S Herter and N J Turner and S L Flitsch and B Hauer},
doi = {10.1039/c6cc01749e},
year = {2016},
date = {2016-01-01},
journal = {Chemical Communications},
volume = {52},
number = {36},
pages = {6158-6161},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Staniland201610755,
title = {Biocatalytic Dynamic Kinetic Resolution for the Synthesis of Atropisomeric Biaryl N-Oxide Lewis Base Catalysts},
author = {S Staniland and R W Adams and J J W McDouall and I Maffucci and A Contini and D M Grainger and N J Turner and J Clayden},
doi = {10.1002/anie.201605486},
year = {2016},
date = {2016-01-01},
journal = {Angewandte Chemie - International Edition},
volume = {55},
number = {36},
pages = {10755-10759},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{deGraaff20161555,
title = {Stereoselective Monoamine Oxidase-Catalyzed Oxidative Aza-Friedel–Crafts Reactions of meso-Pyrrolidines in Aqueous Buffer},
author = {C de Graaff and B Oppelaar and O Péruch and C M L Vande Velde and B Bechi and N J Turner and E Ruijter and R V A Orru},
doi = {10.1002/adsc.201600038},
year = {2016},
date = {2016-01-01},
journal = {Advanced Synthesis and Catalysis},
volume = {358},
number = {10},
pages = {1555-1560},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Özgün2015212,
title = {Characterization of a new acidic NAD+-dependent formate dehydrogenase from thermophilic fungus Chaetomium thermophilum},
author = {G Özgün and N G Karagüler and O Turunen and N J Turner and B Binay},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84944199017&doi=10.1016%2fj.molcatb.2015.09.014&partnerID=40&md5=21bd4f6a48f0fa3e44e411c155bd0e54},
doi = {10.1016/j.molcatb.2015.09.014},
year = {2015},
date = {2015-01-01},
journal = {Journal of Molecular Catalysis B: Enzymatic},
volume = {122},
pages = {212-217},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{ToftgaardPedersen20151580,
title = {Process Requirements of Galactose Oxidase Catalyzed Oxidation of Alcohols},
author = {A Toftgaard Pedersen and W R Birmingham and G Rehn and S J Charnock and N J Turner and J M Woodley},
doi = {10.1021/acs.oprd.5b00278},
year = {2015},
date = {2015-01-01},
journal = {Organic Process Research and Development},
volume = {19},
number = {11},
pages = {1580-1589},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{DeGraaff201514133,
title = {Asymmetric Synthesis of Tetracyclic Pyrroloindolines and Constrained Tryptamines by a Switchable Cascade Reaction},
author = {C De Graaff and L Bensch and S J Boersma and R C Cioc and M J Van Lint and E Janssen and N J Turner and R V A Orru and E Ruijter},
doi = {10.1002/anie.201507041},
year = {2015},
date = {2015-01-01},
journal = {Angewandte Chemie - International Edition},
volume = {54},
number = {47},
pages = {14133-14136},
keywords = {},
pubstate = {published},
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}
@article{Weise201512977,
title = {The bacterial ammonia lyase EncP: A tunable biocatalyst for the synthesis of unnatural amino acids},
author = {N J Weise and F Parmeggiani and S T Ahmed and N J Turner},
doi = {10.1021/jacs.5b07326},
year = {2015},
date = {2015-01-01},
journal = {Journal of the American Chemical Society},
volume = {137},
number = {40},
pages = {12977-12983},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Mutti20151525,
title = {Conversion of alcohols to enantiopure amines through dual-enzyme hydrogen-borrowing cascades},
author = {F G Mutti and T Knaus and N S Scrutton and M Breuer and N J Turner},
doi = {10.1126/science.aac9283},
year = {2015},
date = {2015-01-01},
journal = {Science},
volume = {349},
number = {6255},
pages = {1525-1529},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Kelly20151713,
title = {Active site diversification of P450cam with indole generates catalysts for benzylic oxidation reactions},
author = {P P Kelly and A Eichler and S Herter and D C Kranz and N J Turner and S L Flitsch},
doi = {10.3762/bjoc.11.186},
year = {2015},
date = {2015-01-01},
journal = {Beilstein Journal of Organic Chemistry},
volume = {11},
pages = {1713-1720},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Ahmed20155410,
title = {Chemoenzymatic Synthesis of Optically Pure l- and d-Biarylalanines through Biocatalytic Asymmetric Amination and Palladium-Catalyzed Arylation},
author = {S T Ahmed and F Parmeggiani and N J Weise and S L Flitsch and N J Turner},
doi = {10.1021/acscatal.5b01132},
year = {2015},
date = {2015-01-01},
journal = {ACS Catalysis},
volume = {5},
number = {9},
pages = {5410-5413},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Herter20152313,
title = {Galactose Oxidase Variants for the Oxidation of Amino Alcohols in Enzyme Cascade Synthesis},
author = {S Herter and S M McKenna and A R Frazer and S Leimkühler and A J Carnell and N J Turner},
doi = {10.1002/cctc.201500218},
year = {2015},
date = {2015-01-01},
journal = {ChemCatChem},
volume = {7},
number = {15},
pages = {2313-2317},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{McKenna20153271,
title = {Enzyme cascade reactions: Synthesis of furandicarboxylic acid (FDCA) and carboxylic acids using oxidases in tandem},
author = {S M McKenna and S Leimkühler and S Herter and N J Turner and A J Carnell},
doi = {10.1039/c5gc00707k},
year = {2015},
date = {2015-01-01},
journal = {Green Chemistry},
volume = {17},
number = {6},
pages = {3271-3275},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Man20151052,
title = {Structure, activity and stereoselectivity of NADPH-dependent oxidoreductases catalysing the S-selective reduction of the imine substrate 2-methylpyrroline},
author = {H Man and E Wells and S Hussain and Dr. Leipold F. and S Hart and Dr. Turkenburg J.P. and Prof. Dr. Turner N.J. and G Grogan},
doi = {10.1002/cbic.201402625},
year = {2015},
date = {2015-01-01},
journal = {ChemBioChem},
volume = {16},
number = {7},
pages = {1052-1059},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Faber20151565,
title = {Engineering biocatalysts for synthesis including cascade processes},
author = {K Faber and W -D Fessner and N J Turner},
doi = {10.1002/adsc.201500450},
year = {2015},
date = {2015-01-01},
journal = {Advanced Synthesis and Catalysis},
volume = {357},
number = {8},
pages = {1565-1566},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Parmeggiani20154608,
title = {Synthesis of D- and L-Phenylalanine Derivatives by Phenylalanine Ammonia Lyases: A Multienzymatic Cascade Process},
author = {F Parmeggiani and S L Lovelock and N J Weise and S T Ahmed and N J Turner},
doi = {10.1002/anie.201410670},
year = {2015},
date = {2015-01-01},
journal = {Angewandte Chemie - International Edition},
volume = {54},
number = {15},
pages = {4608-4611},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Knaus2015223,
title = {Systematic methodology for the development of biocatalytic hydrogen-borrowing cascades: Application to the synthesis of chiral α-substituted carboxylic acids from α-substituted α,β-unsaturated aldehydes},
author = {T Knaus and F G Mutti and L D Humphreys and N J Turner and N S Scrutton},
doi = {10.1039/c4ob02282c},
year = {2015},
date = {2015-01-01},
journal = {Organic and Biomolecular Chemistry},
volume = {13},
number = {1},
pages = {223-233},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Hussain2015579,
title = {An (R)-imine reductase biocatalyst for the asymmetric reduction of cyclic imines},
author = {S Hussain and F Leipold and H Man and E Wells and S P France and K R Mulholland and G Grogan and N J Turner},
doi = {10.1002/cctc.201402797},
year = {2015},
date = {2015-01-01},
journal = {ChemCatChem},
volume = {7},
number = {4},
pages = {579-583},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Bechi20144524,
title = {Catalytic bio-chemo and bio-bio tandem oxidation reactions for amide and carboxylic acid synthesis},
author = {B Bechi and S Herter and S McKenna and C Riley and S Leimkühler and N J Turner and A J Carnell},
doi = {10.1039/c4gc01321b},
year = {2014},
date = {2014-01-01},
journal = {Green Chemistry},
volume = {16},
number = {10},
pages = {4524-4529},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Staniland201413084,
title = {Enzymatic Desymmetrising Redox Reactions for the Asymmetric Synthesis of Biaryl Atropisomers},
author = {S Staniland and B Yuan and N Giménez-Agullõ and T Marcelli and S C Willies and D M Grainger and N J Turner and J Clayden},
doi = {10.1002/chem.201404509},
year = {2014},
date = {2014-01-01},
journal = {Chemistry - A European Journal},
volume = {20},
number = {41},
pages = {13084-13088},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Scheller20142201,
title = {Enzyme Toolbox: Novel Enantiocomplementary Imine Reductases},
author = {P N Scheller and S Fademrecht and S Hofelzer and J Pleiss and F Leipold and N J Turner and B M Nestl and B Hauer},
doi = {10.1002/cbic.201402213},
year = {2014},
date = {2014-01-01},
journal = {ChemBioChem},
volume = {15},
number = {15},
pages = {2201-2204},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Schrittwieser20143657,
title = {Deracemisation of benzylisoquinoline alkaloids employing monoamine oxidase variants},
author = {J H Schrittwieser and B Groenendaal and S C Willies and D Ghislieri and I Rowles and V Resch and J H Sattler and E -M Fischereder and B Grischek and W -D Lienhart and N J Turner and W Kroutil},
doi = {10.1039/c4cy00642a},
year = {2014},
date = {2014-01-01},
journal = {Catalysis Science and Technology},
volume = {4},
number = {10},
pages = {3657-3664},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Green201410714,
title = {Chiral amine synthesis using ω-transaminases: An amine donor that displaces equilibria and enables high-throughput screening},
author = {A P Green and N J Turner and E O'Reilly},
doi = {10.1002/anie.201406571},
year = {2014},
date = {2014-01-01},
journal = {Angewandte Chemie - International Edition},
volume = {53},
number = {40},
pages = {10714-10717},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@book{Humphrey2014123,
title = {Application of Enzymes in Kinetic Resolutions, Dynamic Kinetic Resolutions and Deracemization Reactions},
author = {C E Humphrey and M Ahmed and A Ghanem and N J Turner},
doi = {10.1002/9783527650880.ch4},
year = {2014},
date = {2014-01-01},
journal = {Separation of Enantiomers: Synthetic Methods},
volume = {9783527330454},
pages = {123-160},
keywords = {},
pubstate = {published},
tppubtype = {book}
}
@article{Lovelock20144652,
title = {Phenylalanine ammonia lyase catalyzed synthesis of amino acids by an MIO-cofactor independent pathway},
author = {S L Lovelock and R C Lloyd and N J Turner},
doi = {10.1002/anie.201311061},
year = {2014},
date = {2014-01-01},
journal = {Angewandte Chemie - International Edition},
volume = {53},
number = {18},
pages = {4652-4656},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Schrittwieser20143731,
title = {Deracemization by simultaneous bio-oxidative kinetic resolution and stereoinversion},
author = {J H Schrittwieser and B Groenendaal and V Resch and D Ghislieri and S Wallner and E -M Fischereder and E Fuchs and B Grischek and J H Sattler and P MacHeroux and N J Turner and W Kroutil},
doi = {10.1002/anie.201400027},
year = {2014},
date = {2014-01-01},
journal = {Angewandte Chemie - International Edition},
volume = {53},
number = {14},
pages = {3731-3734},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Ghislieri2014284,
title = {Biocatalytic approaches to the synthesis of enantiomerically pure chiral amines},
author = {D Ghislieri and N J Turner},
doi = {10.1007/s11244-013-0184-1},
year = {2014},
date = {2014-01-01},
journal = {Topics in Catalysis},
volume = {57},
number = {5},
pages = {284-300},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Turner2014283,
title = {Foreword},
author = {N J Turner and J Whittall and T R Ward},
doi = {10.1007/s11244-013-0186-z},
year = {2014},
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@book{Turner2014328,
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@article{Zajkoska20141229,
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@article{Ghislieri20132869,
title = {Monoamine oxidase (MAO-N) catalyzed deracemization of tetrahydro-β- carbolines: Substrate dependent switch in enantioselectivity},
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@article{Leipold20133505,
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@article{Ghislieri201310863,
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title = {Structure and activity of NADPH-dependent reductase Q1EQE0 from streptomyces kanamyceticus, which catalyses the R-selective reduction of an imine substrate},
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@book{Turner201363,
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@article{Turner2013212,
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title = {Synthetic cascades are enabled by combining biocatalysts with artificial metalloenzymes},
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@article{KalimAkhtara201387,
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@article{Willies20127564,
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@article{Rowles20121259,
title = {Directed evolution of the enzyme monoamine oxidase (mao-n): Highly efficient chemo-enzymatic deracemisation of the alkaloid (±)-crispinea},
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@article{O'Reilly2012496,
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@article{Foulkes20111589,
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@article{O'Reilly20112490,
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title = {A fast and sensitive assay for measuring the activity and enantioselectivity of transaminases},
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@article{Znabet20107706,
title = {Asymmetric synthesis of synthetic alkaloids by a tandem biocatalysis/Ugi/Pictet-Spengler-type cyclization sequence},
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title = {Efficient production of enantiomerically pure chiral amines at concentrations of 50 g/L using transaminases},
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title = {Engineering and improvement of the efficiency of a chimeric [P450cam-RhFRed reductase domain] enzyme},
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title = {Efficient kinetic resolution of racemic amines using a transaminase in combination with an amino acid oxidase},
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title = {Rapid screening and scale-up of transaminase catalysed reactions},
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title = {Rapid determination of both the activity and enantioselectivity of ketoreductases},
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title = {Preparative deracemization of unnatural amino acids},
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title = {A chemo-enzymatic route to enantiomerically pure cyclic tertiary amines},
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title = {Efficient terpene hydroxylation catalysts based upon P450 enzymes derived from actinomycetes},
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title = {Enantioselective epoxidation of linolenic acid catalysed by cytochrome P450BM3 from Bacillus megaterium},
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title = {Identification of broad specificity P450CAM variants by primary screening against indole as substrate},
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title = {Analysis of the domain properties of the novel cytochrome P450 RhF},
author = {D J B Hunter and G A Roberts and T W B Ost and J H White and S Müller and N J Turner and S L Flitsch and S K Chapman},
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title = {Directed evolution of an amine oxidase for the preparative deracemisation of cyclic secondary amines},
author = {R Carr and M Alexeeva and M J Dawson and V Gotor-Fernández and C E Humphrey and N J Turner},
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title = {Efficient palladium-catalyzed cross-coupling of β-chloroalkylidene/ arylidene malonates using microwave chemistry},
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title = {Rapid identification of cytochrome P450 cam variants by in vivo screening of active site libraries},
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url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-4644247822&doi=10.1016%2fj.tetasy.2004.06.053&partnerID=40&md5=88f8fe2e00f949b5f1b8b7fcf6eb2ffd},
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date = {2004-01-01},
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title = {Rapid and ultra-sensitive determination of enzyme activities using surface-enhanced resonance Raman scattering},
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title = {Dimedone esters as novel hydrolase substrates and their application in the colorimetric detection of lipase and esterase activity},
author = {C E Humphrey and M A M Easson and N J Turner},
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title = {A Versatile Chemo-Enzymatic Route to Enantiomerically Pure β-Branched α-Amino Acids},
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title = {Nucleotide sequence of a portion of the camphor-degrading gene cluster from Rhodococcus sp. NCIMB 9784},
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doi = {10.1080/10425170310001656765},
year = {2004},
date = {2004-01-01},
journal = {DNA Sequence - Journal of DNA Sequencing and Mapping},
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title = {Generation of a dynamic combinatorial library using sialic acid aldolase and in situ screening against wheat germ agglutinin},
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@article{Alexeeva20034133,
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@article{Humphrey200313952,
title = {Lipase-Catalyzed Kinetic Resolution on Solid-Phase via a "Capture and Release" Strategy},
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title = {Directed Evolution of an Amine Oxidase Possessing both Broad Substrate Specificity and High Enantioselectivity},
author = {R Carr and M Alexeeva and A Enright and T S C Eve and M J Dawson and N J Turner},
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@article{Humphrey2003849,
title = {Solid-supported cyclohexane-1,3-dione (CHD): A "capture and release" reagent for the synthesis of amides and novel scavenger resin},
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@article{Hull2003567,
title = {Synthesis of optically active methadones, LAAM and bufuralol by lipase-catalysed acylations},
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title = {A self-sufficient cytochrome p450 with a primary structural organization that includes a flavin domain and a [2Fe-2S] redox center.},
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@article{Lins20023405,
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title = {Amine-boranes: Effective reducing agents for the deracemisation of DL-amino acids using L-amino acid oxidase from Proteus myxofaciens},
author = {F -R Alexandre and D P Pantaleone and P P Taylor and I G Fotheringham and D J Ager and N J Turner},
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title = {Tuning lipase enantioselectivity in organic media using solid-state buffers},
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title = {The desymmetrization of bicyclic β-diketones by an enzymatic retro-Claisen reaction. A new reaction of the crotonase superfamily},
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title = {An asymmetric enzyme-catalyzed retro-claisen reaction for the desymmetrization of cyclic β-diketones},
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date = {1996-01-01},
journal = {Tetrahedron Asymmetry},
volume = {7},
number = {8},
pages = {2185-2188},
keywords = {},
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Lilly, M D; Chauhan, R; French, C; Gyamerah, M; Hobbs, G R; Humphrey, A; Isupov, M; Littlechild, J A; Mitra, R K; Morris, K G; Rupprecht, M; Turner, N J; Ward, J M; Willetts, A J; Woodley, J M
@article{Lilly1996513,
title = {Carbon-carbon bond synthesis: The impact of rDNA technology on the production and use of E. coli transketolase},
author = {M D Lilly and R Chauhan and C French and M Gyamerah and G R Hobbs and A Humphrey and M Isupov and J A Littlechild and R K Mitra and K G Morris and M Rupprecht and N J Turner and J M Ward and A J Willetts and J M Woodley},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029945836&doi=10.1111%2fj.1749-6632.1996.tb40589.x&partnerID=40&md5=469573c9b3a2d818e8464629c06dd58c},
doi = {10.1111/j.1749-6632.1996.tb40589.x},
year = {1996},
date = {1996-01-01},
journal = {Annals of the New York Academy of Sciences},
volume = {782},
pages = {513-525},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Roussel1995933,
title = {Synthesis of shidasterone and the unambiguous determination of its configuration at C-22},
author = {P G Roussel and N J Turner and L N Dinan},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-0342662309&doi=10.1039%2fC39950000933&partnerID=40&md5=6878922b5c2dc428214da56145bc63cb},
doi = {10.1039/C39950000933},
year = {1995},
date = {1995-01-01},
journal = {Journal of the Chemical Society, Chemical Communications},
number = {9},
pages = {933-934},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Humphrey19952475,
title = {Synthesis of enantiomerically pure α-hydroxyaldehydes from the corresponding α-hydroxycarboxylic acids: Novel substrates for Escherichia coli transketolase},
author = {A J Humphrey and N J Turner and R McCague and S J C Taylor},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-37049072050&doi=10.1039%2fC39950002475&partnerID=40&md5=fd3678e1f73bb3a53bc860a72984ac20},
doi = {10.1039/C39950002475},
year = {1995},
date = {1995-01-01},
journal = {Journal of the Chemical Society, Chemical Communications},
number = {24},
pages = {2475-2476},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Stock19952063,
title = {N-(2-carboxybenzoyl)-L-phenylalanylglycine: A low molecular-mass gelling agent},
author = {H T Stock and N J Turner and R McCague},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-37049088306&doi=10.1039%2fC39950002063&partnerID=40&md5=999528dc2027bdda9b9bd3c9355303ab},
doi = {10.1039/C39950002063},
year = {1995},
date = {1995-01-01},
journal = {Journal of the Chemical Society, Chemical Communications},
number = {20},
pages = {2063-2064},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Littlechild19951074,
title = {Crystallization and preliminary X-ray crystallographic data with Escherichia coli transketolase},
author = {J Littlechild and N Turner and G Hobbs and M Lilly and A Rawas and H Watson},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029199270&doi=10.1107%2fS0907444995005415&partnerID=40&md5=2f424cbe6c9d88ea361391674806fbfa},
doi = {10.1107/S0907444995005415},
year = {1995},
date = {1995-01-01},
journal = {Acta Crystallographica Section D: Biological Crystallography},
volume = {51},
number = {6},
pages = {1074-1076},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Brown19951117,
title = {Synthesis of morphine-6-glucuronide via a highly selective enzyme catalysed hydrolysis reaction},
author = {R T Brown and N E Carter and F Scheinmann and N J Turner},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028891801&doi=10.1016%2f0040-4039%2894%2902409-5&partnerID=40&md5=c289b58c4739a311228ba5a2385e6d98},
doi = {10.1016/0040-4039(94)02409-5},
year = {1995},
date = {1995-01-01},
journal = {Tetrahedron Letters},
volume = {36},
number = {7},
pages = {1117-1120},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Turner19951113,
title = {Synthesis of homochiral l-(S)-tert-leucine via a lipase catalysed dynamic resolution process},
author = {N J Turner and J R Winterman and R McCague and J S Parratt and S J C Taylor},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028891799&doi=10.1016%2f0040-4039%2894%2902408-4&partnerID=40&md5=72a2d35f4976140951ad742d1084143e},
doi = {10.1016/0040-4039(94)02408-4},
year = {1995},
date = {1995-01-01},
journal = {Tetrahedron Letters},
volume = {36},
number = {7},
pages = {1113-1116},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Hill19955391,
title = {Revised Pathway for the Biosynthesis of Aristeromycin and Neplanocin A from D-Glucose in Streptomyces citricolor},
author = {J M Hill and G N Jenkins and N J Turner and C P Rush and A J Willetts and A D Buss and M J Dawson and B A M Rudd},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029031673&doi=10.1021%2fja00124a035&partnerID=40&md5=ceb6da5b9a07dc80d615c8641681c9f1},
doi = {10.1021/ja00124a035},
year = {1995},
date = {1995-01-01},
journal = {Journal of the American Chemical Society},
volume = {117},
number = {19},
pages = {5391-5392},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Crosby19941679,
title = {Regioselective hydrolysis of aromatic dinitriles using a whole cell catalyst},
author = {J Crosby and J Moilliet and J S Parratt and N J Turner},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-37049083979&partnerID=40&md5=f168374fe7398a30fe381824a839b7ae},
year = {1994},
date = {1994-01-01},
journal = {Journal of the Chemical Society, Perkin Transactions 1},
number = {13},
pages = {1679-1687},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Hill19941483,
title = {Preparation of neplanocin-A from D-ribose and by a chemoenzymic method},
author = {J M Hill and E J Hutchinson and D M Le Grand and S M Roberts and A J Thorpe and N J Turner},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-37049078947&partnerID=40&md5=0acd57425fe0ea1f8e15f60108e2c8e8},
year = {1994},
date = {1994-01-01},
journal = {Journal of the Chemical Society, Perkin Transactions 1},
number = {11},
pages = {1483-1487},
keywords = {},
pubstate = {published},
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@article{Davey19947867,
title = {Regioselective reduction of substituted dinitroarenes using baker's yeast},
author = {C L Davey and L W Powell and N J Turner and A Wells},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028020841&doi=10.1016%2f0040-4039%2894%2980139-8&partnerID=40&md5=e5f1ffc28cc924e6bf2d82acc02977c1},
doi = {10.1016/0040-4039(94)80139-8},
year = {1994},
date = {1994-01-01},
journal = {Tetrahedron Letters},
volume = {35},
number = {42},
pages = {7867-7870},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Baker19942517,
title = {An improved strategy for the stereoselective synthesis of glycosides using glycosidases as catalysts},
author = {A Baker and N J Turner and M C Webberley},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028020320&doi=10.1016%2fS0957-4166%2800%2980398-5&partnerID=40&md5=2ad61ff0582636b6e941e24e8e807129},
doi = {10.1016/S0957-4166(00)80398-5},
year = {1994},
date = {1994-01-01},
journal = {Tetrahedron: Asymmetry},
volume = {5},
number = {12},
pages = {2517-2522},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Kerridge1994447,
title = {Microbial hydrolysis of glutaronitrile derivatives with brevibacterium sp. R 312},
author = {A Kerridge and J S Parratt and S M Roberts and F Theil and N J Turner and A J Willetts},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028457954&doi=10.1016%2f0968-0896%2894%2980014-6&partnerID=40&md5=991a96529b2a8dce8e6c5cfbe21a9bb3},
doi = {10.1016/0968-0896(94)80014-6},
year = {1994},
date = {1994-01-01},
journal = {Bioorganic and Medicinal Chemistry},
volume = {2},
number = {6},
pages = {447-455},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Pallanca19933017,
title = {Chemo-enzymic synthesis of guanosine 5′-diphosphomannose (GDP-mannose) and selected analogues},
author = {J E Pallanca and N J Turner},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-37049070955&partnerID=40&md5=b67c24dc791422cf9cea58bb07fd8f64},
year = {1993},
date = {1993-01-01},
journal = {Journal of the Chemical Society, Perkin Transactions 1},
number = {23},
pages = {3017-3022},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Brackenridge19931093,
title = {Enzymatic resolution of oxalate esters of a tertiary alcohol using porcine pancreatic lipase},
author = {I Brackenridge and R McCague and S M Roberts and N J Turner},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-37049087848&partnerID=40&md5=ae21ef3d6619b21e093f464b170435be},
year = {1993},
date = {1993-01-01},
journal = {Journal of the Chemical Society, Perkin Transactions 1},
number = {10},
pages = {1093-1094},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Hobbs1993165,
title = {Enzyme-catalysed carbon-carbon bond formation: Use of transketolase from Escherichia coli},
author = {G R Hobbs and M D Lilly and N J Turner and J M Ward and A J Willets and J M Woodley},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-37049067656&partnerID=40&md5=b183acd368303dc88853756c0c7befeb},
year = {1993},
date = {1993-01-01},
journal = {Journal of the Chemical Society, Perkin Transactions 1},
number = {2},
pages = {165-166},
keywords = {},
pubstate = {published},
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@article{Roberts19934083,
title = {The isolation and absolute configuration of (1S,2S,3R)-4- Hydroxymethylcyclopent-4-ene-1,2,3-triol: A putative intermediate in the biosynthesis of aristeromycin by Streptomyces citricolor},
author = {S M Roberts and A J Thorpe and N J Turner and W M Blows and A D Buss and M J Dawson and D Noble and B A M Rudd and P J Sidebottom and W F Wall},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027299439&doi=10.1016%2fS0040-4039%2800%2960621-4&partnerID=40&md5=9f778a246276f8f42eba2683d9249db3},
doi = {10.1016/S0040-4039(00)60621-4},
year = {1993},
date = {1993-01-01},
journal = {Tetrahedron Letters},
volume = {34},
number = {25},
pages = {4083-4086},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Wilson1993195,
title = {A novel mono-branched lipid phosphate acts as a substrate for dolichyl phosphate mannose synthetase},
author = {I B H Wilson and J P Taylor and M C Webberley and N J Turner and S L Flitsch},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027500899&doi=10.1042%2fbj2950195&partnerID=40&md5=3ee57829314f1876a19956bc8be95079},
doi = {10.1042/bj2950195},
year = {1993},
date = {1993-01-01},
journal = {Biochemical Journal},
volume = {295},
number = {1},
pages = {195-201},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Beard19931085,
title = {Stereoselective hydrolysis of nitriles and amides under mild conditions using a whole cell catalyst},
author = {T Beard and M A Cohen and J S Parratt and N J Turner and J Crosby and J Moilliet},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027159507&doi=10.1016%2fS0957-4166%2800%2980215-3&partnerID=40&md5=39d59e135b20e3e0d026f1270553c8c2},
doi = {10.1016/S0957-4166(00)80215-3},
year = {1993},
date = {1993-01-01},
journal = {Tetrahedron: Asymmetry},
volume = {4},
number = {6},
pages = {1085-1104},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Floyd19921085,
title = {A simple strategy for obtaining both enantiomers from an aldolase reaction: Preparation of L- and D-4-hydroxy-2-ketoglutarate},
author = {N C Floyd and M H Liebster and N J Turner},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-37049090311&partnerID=40&md5=acd6c4d7eeb6bbe602f2f45ff4b74be5},
year = {1992},
date = {1992-01-01},
journal = {Journal of the Chemical Society, Perkin Transactions 1},
number = {9},
pages = {1085-1086},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Flitsch19922087,
title = {Chemo-enzymatic synthesis of a lipid-linked core trisaccharide of N-linked glycoproteins},
author = {S L Flitsch and H L Pinches and J P Taylor and N J Turner},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-37049081808&partnerID=40&md5=d664880c09f9b1ac31322eeb7311f146},
year = {1992},
date = {1992-01-01},
journal = {Journal of the Chemical Society, Perkin Transactions 1},
number = {16},
pages = {2087-2093},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Chinn1992661,
title = {Regioselective enzymatic acetylation of methyl 4,6-O-benzylidene-α- and β-D-glucopyranoside},
author = {M J Chinn and G Iacazio and D G Spackman and N J Turner and S M Roberts},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-37049066543&partnerID=40&md5=bda086758a81aef4802fb5cfcc347c68},
year = {1992},
date = {1992-01-01},
journal = {Journal of the Chemical Society, Perkin Transactions 1},
number = {6},
pages = {661-662},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Chinn19922045,
title = {Erratum: Regioselective enzymatic acetylation of methyl 4,6-O-benzylidene-α- and β-D-glucopyranoside (Journal of the Chemical Society, Perkin Transactions 1 (1992), (661))},
author = {M J Chinn and G Iacazio and D G Spackman and N J Turner and S M Roberts},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-37049075750&partnerID=40&md5=25685aca9c7c8b88a3e197d0886078b9},
year = {1992},
date = {1992-01-01},
journal = {Journal of the Chemical Society, Perkin Transactions 1},
number = {15},
pages = {2045},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Roberts1992227,
title = {Some recent developments in the use of enzyme catalysed reactions in organic synthesis},
author = {S M Roberts and N J Turner},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026565323&doi=10.1016%2f0168-1656%2892%2990143-W&partnerID=40&md5=bcce1c1f914c0876f2c5e225d4032e92},
doi = {10.1016/0168-1656(92)90143-W},
year = {1992},
date = {1992-01-01},
journal = {Journal of Biotechnology},
volume = {22},
number = {3},
pages = {227-244},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Cohen19921543,
title = {Enantioselective hydrolysis of nitriles and amides using an immobilised whole cell system},
author = {M A Cohen and J S Parratt and N J Turner},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026677853&doi=10.1016%2fS0957-4166%2800%2986056-5&partnerID=40&md5=82864902a257c739d37f2bdd1de064b8},
doi = {10.1016/S0957-4166(00)86056-5},
year = {1992},
date = {1992-01-01},
journal = {Tetrahedron: Asymmetry},
volume = {3},
number = {12},
pages = {1543-1546},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Baldwin19919881,
title = {Cephalosporin biosynthesis: A branched pathway sensitive to an isotope effect},
author = {J E Baldwin and R M Adlington and N P Crouch and C J Schofield and N J Turner and R T Aplin},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026045410&doi=10.1016%2fS0040-4020%2801%2980725-0&partnerID=40&md5=a26fda5575fda3a5194bb230b7627f45},
doi = {10.1016/S0040-4020(01)80725-0},
year = {1991},
date = {1991-01-01},
journal = {Tetrahedron},
volume = {47},
number = {47},
pages = {9881-9900},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Turner19911349,
title = {Stereospecific attachment of carbohydrates to amino acid derivatives using β-glucosidase and β-xylosidase},
author = {N J Turner and M C Webberley},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025914302&doi=10.1039%2fC39910001349&partnerID=40&md5=b9d6deab6cf540576a564683515e12ce},
doi = {10.1039/C39910001349},
year = {1991},
date = {1991-01-01},
journal = {Journal of the Chemical Society, Chemical Communications},
number = {19},
pages = {1349-1350},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Flitsch1991380,
title = {Synthesis of a novel acceptor substrate for a mannosyl transferase},
author = {S L Flitsch and J P Taylor and N J Turner},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-7844240161&doi=10.1039%2fC39910000380&partnerID=40&md5=7ad148fe16fe7f795e15a2372cebb967},
doi = {10.1039/C39910000380},
year = {1991},
date = {1991-01-01},
journal = {Journal of the Chemical Society, Chemical Communications},
number = {6},
pages = {380-382},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Flitsch1991382,
title = {Chemo-enzymatic synthesis of a β-mannosyl-containing trisaccharide},
author = {S L Flitsch and J P Taylor and N J Turner},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-10544250217&doi=10.1039%2fC39910000382&partnerID=40&md5=1ca252e1afabf3323891495c680aa08c},
doi = {10.1039/C39910000382},
year = {1991},
date = {1991-01-01},
journal = {Journal of the Chemical Society, Chemical Communications},
number = {6},
pages = {382-384},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Baldwin19918223,
title = {Enzymic conversion of deuterated analogues of δ-l-α-aminoadipoyl-l-cysteinyl-d-allylglycine, an unnatural substrate for isopenicilin n synthase: A unified theory of second ring closure.},
author = {J E Baldwin and M Bradley and N J Turner and R M Adlington and A R Pitt and A E Derome},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025994422&doi=10.1016%2fS0040-4020%2801%2991016-6&partnerID=40&md5=29a0a9a70baa16eb38e81719141e3875},
doi = {10.1016/S0040-4020(01)91016-6},
year = {1991},
date = {1991-01-01},
journal = {Tetrahedron},
volume = {47},
number = {38},
pages = {8223-8242},
keywords = {},
pubstate = {published},
tppubtype = {article}
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@article{Baldwin19918203,
title = {Synthesis of δ-L-α-aminoadipoyl-L-cysteinyl-D-allylglycine, and eight deuterated analogues, substrates for the investigation of the mechanism of action of isopenicillin n synthase.},
author = {J E Baldwin and M Bradley and N J Turner and R M Adlington and A R Pitt and H Sheridan},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026045350&doi=10.1016%2fS0040-4020%2801%2991015-4&partnerID=40&md5=e35c72ccc1e5c79180b60feac000328f},
doi = {10.1016/S0040-4020(01)91015-4},
year = {1991},
date = {1991-01-01},
journal = {Tetrahedron},
volume = {47},
number = {38},
pages = {8203-8222},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Macfarlane199113,
title = {Some interesterification reactions involving mucor miehei lipase},
author = {E L A Macfarlane and F Rebolledo and S M Roberts and N J Turner},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-0002591093&doi=10.3109%2f10242429109014851&partnerID=40&md5=a2d15eff3ada5cd940202ab902c289c1},
doi = {10.3109/10242429109014851},
year = {1991},
date = {1991-01-01},
journal = {Biocatalysis and Biotransformation},
volume = {5},
number = {1},
pages = {13-19},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Baldwin1991457,
title = {Further evidence for the involvement of a monocyclic β-lactam in the enzymatic conversion of δ-L-α-aminoadipoyl-L-cysteinyl-D-valine into isopenicillin N.},
author = {J E Baldwin and M Bradley and R M Adlington and W J Norris and N J Turner},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025968688&doi=10.1016%2fS0040-4020%2801%2990503-4&partnerID=40&md5=9f3297988308d48309353029de5ec2c8},
doi = {10.1016/S0040-4020(01)90503-4},
year = {1991},
date = {1991-01-01},
journal = {Tetrahedron},
volume = {47},
number = {3},
pages = {457-480},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{MacFarlane1990569,
title = {Enzyme-catalysed inter-esterification procedure for the preparation of esters of a chiral secondary alcohol in high enantiomeric purity},
author = {E L A MacFarlane and S M Roberts and N J Turner},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-37049085076&doi=10.1039%2fC39900000569&partnerID=40&md5=41a70d5ff702d779e3f9679af8aa01b7},
doi = {10.1039/C39900000569},
year = {1990},
date = {1990-01-01},
journal = {Journal of the Chemical Society, Chemical Communications},
number = {7},
pages = {569-571},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Cohen19907223,
title = {Selective hydrolysis of nitriles under mild conditions by an enzyme.},
author = {M A Cohen and J Sawden and N J Turner},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025662001&doi=10.1016%2fS0040-4039%2800%2997285-X&partnerID=40&md5=06eaaa0ed18b0dca82d694e42f045639},
doi = {10.1016/S0040-4039(00)97285-X},
year = {1990},
date = {1990-01-01},
journal = {Tetrahedron Letters},
volume = {31},
number = {49},
pages = {7223-7226},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Turner1989624,
title = {A Combined Chemical—Enzymatic Synthesis of 3-Deoxy-D-arabino-heptulosonic Acid 7-Phosphate},
author = {N J Turner and G M Whitesides},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-0001566797&doi=10.1021%2fja00184a033&partnerID=40&md5=dbe5581ea62bd4da27169af7b7b4f906},
doi = {10.1021/ja00184a033},
year = {1989},
date = {1989-01-01},
journal = {Journal of the American Chemical Society},
volume = {111},
number = {2},
pages = {624-627},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Baldwin19891141,
title = {Cephalosporin C biosynthesis; stereochemistry of the incorporation of D,L,D-α-aminodipoyl-cysteinyl-(3S)-[2-2H,4-13C] valine into β-lactam compounds},
author = {J E Baldwin and R M Adlington and N P Crouch and N J Turner and C J Schofield},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-0024392685&doi=10.1039%2fC39890001141&partnerID=40&md5=2e88449c60872eb2d281c7e0ef175f8e},
doi = {10.1039/C39890001141},
year = {1989},
date = {1989-01-01},
journal = {Journal of the Chemical Society, Chemical Communications},
number = {16},
pages = {1141-1143},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Baldwin1989978,
title = {Evidence for epoxide formation from isopenicillin N synthase},
author = {J E Baldwin and R M Adlington and M Bradley and N J Turner and A R Pitt},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-37049088151&doi=10.1039%2fC39890000978&partnerID=40&md5=ac80ed526f0e6b90283fe81003b1870b},
doi = {10.1039/C39890000978},
year = {1989},
date = {1989-01-01},
journal = {Journal of the Chemical Society, Chemical Communications},
number = {15},
pages = {978-981},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Baldwin1989802,
title = {Penicillin biosynthesis: Active substrates derived by methoxy substitution in the valinyl residue of the natural substrate},
author = {J E Baldwin and R M Adlington and A Basak and P Imming and K Ponnamperuma and H Ronneberg and C J Schofield and H Ting and N J Turner},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-0024392313&doi=10.1039%2fC39890000802&partnerID=40&md5=af1335458b7abd1a982560766069cc30},
doi = {10.1039/C39890000802},
year = {1989},
date = {1989-01-01},
journal = {Journal of the Chemical Society, Chemical Communications},
number = {12},
pages = {802-804},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Baldwin19881125,
title = {Identification and characterisation of shunt metabolites from isopenicillin N synthase},
author = {J E Baldwin and R M Adlington and M Bradley and W J Norris and N J Turner and A Yoshida},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-37049080389&doi=10.1039%2fC39880001125&partnerID=40&md5=4928d5ee69fa45d15508c09c9f6f0370},
doi = {10.1039/C39880001125},
year = {1988},
date = {1988-01-01},
journal = {Journal of the Chemical Society, Chemical Transactions},
number = {16},
pages = {1125-1128},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Baldwin19881125b,
title = {Identification and characterisation of shunt metabolites from isopenicillin N synthase},
author = {J E Baldwin and R M Adlington and M Bradley and W J Norris and N J Turner and A Yoshida},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023789386&doi=10.1039%2fc39880001125&partnerID=40&md5=f817859ad51287c144f6408e363287d9},
doi = {10.1039/c39880001125},
year = {1988},
date = {1988-01-01},
journal = {Journal of the Chemical Society - Series Chemical Communications},
number = {16},
pages = {1125-1128},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Baldwin1987652,
title = {Purification and characterization of cloned isopenicillin N synthetase},
author = {J E Baldwin and A J Pratt and J D Sutherland and N J Turner and M J Crabbe},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023180606&doi=10.7164%2fantibiotics.40.652&partnerID=40&md5=772235131cbb52691e86f6107dd0e732},
doi = {10.7164/antibiotics.40.652},
year = {1987},
date = {1987-01-01},
journal = {The Journal of Antibiotics},
volume = {40},
number = {5},
pages = {652-659},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Baldwin1986110,
title = {Stereospecificity of carbon-sulphur bond formation in penicillin biosynthesis},
author = {J E Baldwin and R M Adlington and B P Domayne-Hayman and H -H Ting and N J Turner},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-0022909108&doi=10.1039%2fC39860000110&partnerID=40&md5=30c1bcb2bbfb60b55f9f1c6fc83db728},
doi = {10.1039/C39860000110},
year = {1986},
date = {1986-01-01},
journal = {Journal of the Chemical Society, Chemical Communications},
number = {2},
pages = {110-113},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Baldwin19861305,
title = {Penicillin biosynthesis: The origin of hydroxy groups in β-lactams derived from unsaturated substrates},
author = {J E Baldwin and R M Adlington and S L Flitsch and H -H Ting and N J Turner},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-0022917323&doi=10.1039%2fC39860001305&partnerID=40&md5=8d962684c46982bfdb487d3107a7c78c},
doi = {10.1039/C39860001305},
year = {1986},
date = {1986-01-01},
journal = {Journal of the Chemical Society, Chemical Communications},
number = {17},
pages = {1305-1308},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Baldwin1986975,
title = {Enzymatic synthesis of a new type of penicillin},
author = {J E Baldwin and R M Adlington and A Basak and S L Flitsch and S Petursson and N J Turner and H -H Ting},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-0022869537&doi=10.1039%2fC39860000975&partnerID=40&md5=74063d0835e546b188b79e0b377e4b2d},
doi = {10.1039/C39860000975},
year = {1986},
date = {1986-01-01},
journal = {Journal of the Chemical Society, Chemical Communications},
number = {12},
pages = {975-976},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Baldwin19841211,
title = {Penicillin biosynthesis: Multiple pathways from a modified substrate},
author = {J E Baldwin and R M Adlington and A E Derome and H -H Ting and N J Turner},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-0021151866&doi=10.1039%2fC39840001211&partnerID=40&md5=4cebffe66e4fe9cd354bd92e36af6250},
doi = {10.1039/C39840001211},
year = {1984},
date = {1984-01-01},
journal = {Journal of the Chemical Society, Chemical Communications},
number = {18},
pages = {1211-1214},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
@article{Baldwin19841167,
title = {Penicillin biosynthesis: Enzymatic synthesis of new cephams},
author = {J E Baldwin and R M Adlington and N J Turner and B P Domayne-Hayman and H -H Ting and A E Derome and J A Murphy},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-0021233170&doi=10.1039%2fc39840001167&partnerID=40&md5=2b6c1821a562f5fb030d4a4de77e71a5},
doi = {10.1039/c39840001167},
year = {1984},
date = {1984-01-01},
journal = {Journal of the Chemical Society, Chemical Communications},
number = {17},
pages = {1167-1170},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Baldwin, J E; Abraham, E P; Adlington, R M; Bahadur, G A; Chakravarti, B; Domayne-Hayman, B P; Field, L D; Flitsch, S L; Jayatilake, G S; Špakovskis, A; Ting, H -H; Turner, N J; White, R L; Usher, J J
@article{Baldwin19841225,
title = {Penicillin biosynthesis: Active site mapping with aminoadipoylcysteinylvaline variants},
author = {J E Baldwin and E P Abraham and R M Adlington and G A Bahadur and B Chakravarti and B P Domayne-Hayman and L D Field and S L Flitsch and G S Jayatilake and A Špakovskis and H -H Ting and N J Turner and R L White and J J Usher},
url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-0021210866&doi=10.1039%2fC39840001225&partnerID=40&md5=c6c15410e63f10712b2e1de3e70277c4},
doi = {10.1039/C39840001225},
year = {1984},
date = {1984-01-01},
journal = {Journal of the Chemical Society, Chemical Communications},
number = {18},
pages = {1225-1227},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
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